Ohio Wesleyan took a 1-0 lead in the first half with a goal in the final minute of the period, then added a second goal in the 66th minute to secure the win.
Dan Schubert (Lebanon, IL/Lebanon) and Tom Reifenberg (Ft. Wayne, IN/Bishop Dwenger) each managed shots on goal for Wabash.
Wabash is 4-8-2, 2-5-1 in North Coast Athletic Conference play. The Little Giants will end their season with a conference match at 1 p.m. on Saturday at Oberlin.